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Biomarkers to detect central dopamine deficiency and distinguish Parkinson disease from multiple system atrophy

2008; Elsevier BV; Volume: 14; Issue: 8 Linguagem: Inglês

10.1016/j.parkreldis.2008.01.010

1873-5126

David S. Goldstein, Courtney Holmes, Oladi Bentho, Takuya Sato, Jeffrey P. Moak, Yehonatan Sharabi, Richard Imrich, Shielah Conant, Basil A. Eldadah,

Neurological disorders and treatments

Biomarkers are increasingly important to diagnose and test treatments of neurodegenerative diseases such as Parkinson disease (PD). This study compared neuroimaging, neurochemical, and olfactory potential biomarkers to detect central dopamine (DA) deficiency and distinguish PD from multiple system atrophy (MSA).