How pure are our inbred strains of mice?
1960; Cambridge University Press; Volume: 1; Issue: 1 Linguagem: Inglês
10.1017/s0016672300000069
ISSN1469-5073
AutoresM. S. Deol, Hans Grüneberg, A.G. Searle, Gillian M. Truslove,
Tópico(s)Genetic Mapping and Diversity in Plants and Animals
ResumoSixty-six individual tests on an array of skeletal variants showed an essential absence of parent-offspring correlations in the inbred strains C57BL, A and CBA in the mouse. It is concluded that these strains, and inbred strains of mice in general, are genetically homogeneous except for the differentiation of genetically distinct sublines as the result of mutations.
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