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Whole Blood Gene Expression Profiles to Assess Pathogenesis and Disease Severity in Infants with Respiratory Syncytial Virus Infection

2013; Public Library of Science; Volume: 10; Issue: 11 Linguagem: Inglês

10.1371/journal.pmed.1001549

1549-1676

Asunción Mejías, Blerta Dimo, Nicolás M. Suárez, Carla García, M. Carmen Suárez-Arrabal, Tuomas Jartti, Derek Blankenship, Alejandro Jordán-Villegas, Monica I. Ardura, Zhaohui Xu, Jacques Banchereau, Damien Chaussabel, Octavio Ramilo,

Neonatal Respiratory Health Research

In this study, Mejias and colleagues found that specific blood RNA profiles of infants with RSV LRTI allowed for specific diagnosis, better understanding of disease pathogenesis, and better assessment of disease severity. Please see later in the article for the Editors' Summary