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Incidence of childhood-onset Type I diabetes in Slovenia and the Tuzla region (Bosnia and Herzegovina) in the period 1990 –1998

2001; Springer Science+Business Media; Volume: 44; Issue: S3 Linguagem: Inglês

10.1007/pl00002949

1432-0428

Nataša Bratina, Husref Tahirović, Tadej Battelino, Ciril Kržišnik,

Diabetes Management and Research

The incidence rate of childhood-onset Type I (insulin-dependent) diabetes mellitus in Slovenian children during the period 1990–1998 was studied and compared to that of children from the Tuzla region (Bosnia and Herzegovina). The secular trend for a 25-year period in Slovenia was also investigated. The incidence data were obtained from the national Slovenian Type I diabetes register and from the local Type I diabetes register held in Tuzla. The ascertainment was based on the capture – recapture method and was estimated to be 100 %. The age-standardized incidence of Type I diabetes mellitus for the age group 0–14 years for Slovenia was 8.54 per 100 000 (95 %-C.I. 7.5–9.5) person-years for both sexes. The incidence for boys was 8.03 per 100 000 (95 %-C.I. 6.7–9.4) and 9.12 per 100 000 (95 %-C.I. 7.6–10.6) for girls. The age-standardized incidence in the Tuzla region was much lower: 3.03 per 100 000 (95 %-C.I. 2.0–4.1) for the whole group, 3.44 per 100 000 (95 %-C.I. 1.8–5.0) for boys and 3.21 per 100 000 (95 %-C.I. 1.6–4.7) for girls. A very low incidence of 0.8 per 100 000 in the youngest age group (0–4 years) was observed in the Tuzla region. The linear trend of the Type I diabetes incidence rate in Slovenia has been steadily increasing by 3.6 % per year for the last 25 years. The incidence rate in the period 1974–1985 was significantly lower than that in the period 1986–1998 (p < 0.00 026). Although the incidence rate in Slovenia slightly increased during the period 1990–1998, the incidence rate in the Tuzla region remained at the pre-war level. [Diabetologia (2001) 44 [Suppl 3]: B 27–B 31]