Portal de Periódicos da CAPES

Circular dichroism studies on repeating polypeptide sequences of abductin

2005; Wiley; Volume: 17; Issue: 7 Linguagem: Inglês

10.1002/chir.20172

1520-636X

Brigida Bochicchio, Antonietta Pepe, Antonio Mario Tamburro,

Enzyme Structure and Function

ChiralityVolume 17, Issue 7 p. 364-372 Regular Article/Dedicated to Prof. Piero Salvadori Circular dichroism studies on repeating polypeptide sequences of abductin† Brigida Bochicchio, Brigida Bochicchio Department of Chemistry, Università degli Studi della Basilicata, Potenza, ItalySearch for more papers by this authorAntonietta Pepe, Antonietta Pepe Department of Chemistry, Università degli Studi della Basilicata, Potenza, ItalySearch for more papers by this authorAntonio M. Tamburro, Corresponding Author Antonio M. Tamburro [email protected] Department of Chemistry, Università degli Studi della Basilicata, Potenza, ItalyDepartment of Chemistry, Università della Basilicata, Via Nazario Sauro, 85, 85100 Potenza, ItalySearch for more papers by this author Brigida Bochicchio, Brigida Bochicchio Department of Chemistry, Università degli Studi della Basilicata, Potenza, ItalySearch for more papers by this authorAntonietta Pepe, Antonietta Pepe Department of Chemistry, Università degli Studi della Basilicata, Potenza, ItalySearch for more papers by this authorAntonio M. Tamburro, Corresponding Author Antonio M. Tamburro [email protected] Department of Chemistry, Università degli Studi della Basilicata, Potenza, ItalyDepartment of Chemistry, Università della Basilicata, Via Nazario Sauro, 85, 85100 Potenza, ItalySearch for more papers by this author First published: 29 June 2005 https://doi.org/10.1002/chir.20172Citations: 13 † Abbreviations: Boc, tert-butyloxycarbonyl; DCC, dicyclohexyl carbodiimide; Fmoc, 9-fluorenyl-methoxycarbonyl; G, glycine; HOBt, hydroxybenzotriazole; IBCF, isobutylchloroformate; M, methionine; NMM, N-methylmorpholine; OEt, ethyl ester; TFA, trifluoroacetic acid AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Abstract The secondary structure of abductin was investigated by CD and NMR studies of several synthetic peptides. Results obtained with these peptides showed the dominant conformations to be the polyproline II (PPII) structure in aqueous solution and different types of β-turns in the less polar solvent trifluoroethanol. Accordingly, a preliminary structure–elasticity relationship for abductin, not unlike that currently accepted for elastin, is proposed. Chirality 17:364–372, 2005. © 2005 Wiley-Liss, Inc. Citing Literature Volume17, Issue72005Pages 364-372 RelatedInformation