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BIBTEX RIS

Turmeric ( Curcuma longa L.) volatile oil inhibits key enzymes linked to type 2 diabetes

2012; Taylor & Francis; Volume: 63; Issue: 7 Linguagem: Inglês

10.3109/09637486.2011.607156

ISSN

1465-3478

Autores

P Lekshmi, Ranjith Arimboor, P. S. Indulekha, A. Nirmala Menon,

Tópico(s)

Biochemical Analysis and Sensing Techniques

Resumo

Anti-diabetic capacity of Curcuma longa volatile oil in terms of its ability to inhibit glucosidase activities was evaluated. Turmeric volatile oils inhibited glucosidase enzymes more effectively than the reference standard drug acarbose. Drying of rhizomes was found to enhance α-glucosidase (IC50 = 1.32–0.38 μg/ml) and α-amylase (IC50 = 64.7–34.3 μg/ml) inhibitory capacities of volatile oils. Ar-Turmerone, the major volatile component in the rhizome also showed potent α-glucosidase (IC50 = 0.28 μg) and α-amylase (IC50 = 24.5 μg) inhibition.

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