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Basic principles for compounding all-in-one parenteral nutrition admixtures

1998; Lippincott Williams & Wilkins; Volume: 1; Issue: 3 Linguagem: Inglês

10.1097/00075197-199805000-00010

1473-6519

Gil Hardy, Patrick Ball, B. McElroy,

Electrolyte and hormonal disorders

Parenteral nutrition admixtures are complex pharmaceutical entities. The more closely they are examined, the more physico-chemical interactions emerge that could potentially affect stability. The move towards large scale hospital or commercial preparation, with a requirement for extended shelf life, and the increasing use of admixtures as vehicles for drugs and pharmaconutrients have created new formulation challenges for pharmaceutical scientists.