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Artigo Revisado por pares
BIBTEX RIS

Pharmacological profile and chemical synthesis of SR 48968, a non-peptide antagonist of the neurokinin A (NK2) receptor

1993; Elsevier BV; Volume: 3; Issue: 5 Linguagem: Inglês

10.1016/s0960-894x(00)80694-0

ISSN

1464-3405

Autores

Xavier Emonds‐Alt, Vincenzo Proietto, Didier Van Broeck, P. Vilain, Charles Advenier, G. Néliat, Gérard Le Fur, Jean-Claude Brelère,

Tópico(s)

Eicosanoids and Hypertension Pharmacology

Resumo

SR 48968 is a potent, competitive and selective non-peptide antagonist of the neurokinin A (NK2)_receptor. The synthesis of SR 48968 is described. Structure activity relationship is shown using binding and pharmacological results.

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