Multicenter Automatic Defibrillator Implantation Trial–Cardiac Resynchronization Therapy (MADIT‐CRT): Design and Clinical Protocol
2005; Wiley; Volume: 10; Issue: s4 Linguagem: Inglês
10.1111/j.1542-474x.2005.00073.x
ISSN1542-474X
AutoresArthur J. Moss, Mary W. Brown, David S. Cannom, James P. Daubert, Mark Estes, Elyse Foster, Henry Greenberg, William J. Hall, Steven L. Higgins, Helmut Klein, Mark A Pfeffer, David J. Wilber, Wojciech Zaręba,
Tópico(s)Cardiac electrophysiology and arrhythmias
ResumoThe planned MADIT‐CRT trial is designed to determine if CRT‐D will reduce the risk of mortality and HF events by approximately 25% in subjects with ischemic (NYHA class I‐II) and non‐ischemic (NYHA class II) cardiomyopathy, left ventricular dysfunction (EF ≤ 0.30), and prolonged intraventricular conduction (QRS duration ≥ 130 ms).
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