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A SIMPLE METHOD FOR ESTIMATING 24 H URINARY SODIUM AND POTASSIUM EXCRETION FROM SECOND MORNING VOIDING URINE SPECIMEN IN ADULTS

1993; Wiley; Volume: 20; Issue: 1 Linguagem: Inglês

10.1111/j.1440-1681.1993.tb01496.x

1440-1681

Terukazu Kawasaki, Kazue Itoh, Keiko Uezono, Haruka Sasaki,

Renal function and acid-base balance

SUMMARY 1. An assessment was made of the extent sodium (Na) and potassium (K) intake can be estimated from Na, K and creatinine (Cr) content of a second morning voiding urine (SMU) specimen collected within 4 h after the first voiding upon awakening but before breakfast in 159 clinically healthy, free‐living individuals (20–79 years). The SMU and the rest of 24 h urine specimens for a 3–5 day period were collected. 2. The following equations for estimating 24 h urinary Na (24HU Na V) and K (24HU K V) excretions were developed, and the accuracy and the reliability of these equations were evaluated. Estimated value of 24HU Na V (mEq/day) = 16.3 √X Na ; estimated value of 24HU K V (mEq/day) = 7.2 √X K , where X Na (or X K ) = SMU Na (or SMU K )/SMU Cr X predicted 24 h urinary Cr excretion. 3. Highly statistically significant correlations were detected between the values estimated and measured for both Na ( r = 0.728, P < 0.001, n = 159) and K ( r = 0.780, P < 0.001, n = 159). 4. These equations were applied to Group 1 subjects, who collected the urine for a single day, and to Group 2, for 3 days. The correlation coefficients between the values estimated and measured for Na and K were 0.531 and 0.443 in Group 1, and 0.821 and 0.590 in Group 2, respectively. No statistically significant differences were observed. 5. The SMU specimens provide a satisfactory alternative to both 24HU Na V and 24HU K V in adults for extensive epidemiological surveys but also for clinical application.