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Translocation (X;1) reveals metastasis 31 years after renal cell carcinoma

1998; Elsevier BV; Volume: 101; Issue: 1 Linguagem: Inglês

10.1016/s0165-4608(97)00063-0

1873-4456

Paola Dal Cin, Marguerite Stas, Raf Sciot, Ivo De Wever, Boudewijn Van Damme, Herman Van den Berghe,

Cancer Genomics and Diagnostics

Abstract Cytogenetic investigation of a metastatic lesion appearing 31 years after nephrectomy allowed for the diagnosis of a renal cell carcinoma. The der(X)t(X1)(p11.2;q21.1) found in this case and review of the 14 other cases previously reported indicates that this chromosome lesion may characterize a specific subgroup of renal cell carcinoma, with distinct histology and age distribution that also can occur in females.