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Drug-induced lupus erythematosus

2004; Elsevier BV; Volume: 22; Issue: 2 Linguagem: Inglês

10.1016/j.clindermatol.2003.12.023

1879-1131

Dimitar Antonov, Jana Kazandjieva, Doncho Etugov, Dimitar Gospodinov, Nikolaï Tsankov,

Blood disorders and treatments

Among the numerous idiopathic immune-mediated diseases that can be drug-induced, such as pemphigus, psoriasis, lichen, etc, drug-induced lupus is the most widely commented upon and investigated. The terms drug-induced lupus (DIL) and drug-induced lupus erythematosus (DILE) are preferred, but other ones are also used—drug-related lupus, lupus-like syndrome, and lupus erythematosus medicamentosus.1 This review discusses the general issues in DILE, such as pathogenic mechanisms, clinical forms, and diagnostic criteria, and provides more detailed information for some of the implicated drugs: minocycline, statins, terbinafine, etc.