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Antioxidant phenolic and quinonemethide triterpenes from Cheiloclinium cognatum

2004; Elsevier BV; Volume: 65; Issue: 13 Linguagem: Inglês

10.1016/j.phytochem.2004.03.039

1873-3700

Alex Haroldo Jeller, Dulce Helena Siqueira Silva, Luciano M. Lião, Vanderlan da Silva Bolzani, Maysa Furlan,

Phytochemical compounds biological activities

The triterpenes, 22β-hydroxypristimerin and cognatine, were isolated together with the known compounds pristimerin, maytenin, 20α-hydroxymaytenin, 22β-hydroxymaytenin, netzahualcoyol, netzahualcoyondiol and netzahualcoyone from root bark of Cheiloclinium cognatum. The structures of the isolated compounds were elucidated by interpretation of their spectral data, including gHMQC and gHMBC experiments.The isolates were investigated for their radical scavenging abilities through a spectrophotometric assay involving reduction of 2,2-diphenyl-picryl hydrazyl (DPPH).