Biochemistry of major human histocompatibility antigens

1980; Elsevier BV; Volume: 1; Issue: 6 Linguagem: Inglês

10.1016/0167-5699(80)90048-1

ISSN

1355-8242

Autores

Michael J. Owen, Michaël J. Crumpton,

Tópico(s)

Immune Cell Function and Interaction

Resumo

The major histocompatibility region, designated HLA in man and H-2 in the mouse, controls the expression of at least three groups of gene product - serum complement components and two sets of highly polymorphic cell-surface antigens, the so called histocompatibility antigens. In this review Michael Owen and Michael Crumpton describe some recent insights into the biochemical structure of HLA antigens.

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