A Study of Topical Therapy in Tinea Capitis
1952; Elsevier BV; Volume: 19; Issue: 3 Linguagem: Inglês
10.1038/jid.1952.82
ISSN1523-1747
AutoresMAURICE SULLIVAN, EUGENE S. BERESTON,
Tópico(s)Fungal Infections and Studies
ResumoThirteen treatment agents (Table 1) were evaluated in eight huiidred eightyone clinical trials in 460 patients (Table 2).Prior to treatment fluorescence in infected areas was detected with the Wood's Light and cultures of fluorescent hair were made; 83.2% were positive for M. audouini, 1.0% were positive for M. lanosum and 15.7% showed rio growth or were contaminated.Each compound was used for at least three months before it was considered ineffective.Medication was applied twice a day and hair was clipped once a week.Manual epilation was not allowed.Examination were made every two weeks.Cure was determined by disappearance of fluorescence in infected areas, regrowth of normal hair and absence of fluorescence for 90 days after termination of treatment.The results are summarized in Table 3.The 75% cure rate in the group of 132 patients treated
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