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Composição química e atividade biológica de extrato oleoso de própolis: uma alternativa ao extrato etanólico

2009; Brazilian Chemical Society; Volume: 32; Issue: 2 Linguagem: Inglês

10.1590/s0100-40422009000200006

ISSN

1678-7064

Autores

Lilian Buriol, Daiane Finger, Eduardo Morgado Schmidt, Julio Murilo Trevas dos Santos, Marcos Roberto da Rosa, Sueli Pércio Quináia, Yohandra Reyes Torres, Herta Stutz Dalla Santa, Cláudia Pessoa, Manoel Odorico de Moraes, Letícia V. Costa‐Lotufo, Paulo Michel Pinheiro Ferreira, Alexandra Christine Helena Frankland Sawaya, Marcos N. Eberlin,

Tópico(s)

Essential Oils and Antimicrobial Activity

Resumo

EXTRACT: AN ALTERNATIVE TO ETHANOLIC EXTRACT.Propolis is mostly used as hydroalcoholic extract.Recently there has been a growing number of patents dealing with new solvents for preparing propolis extracts.This study aimed to prepare edible oil propolis extracts and compare their chemical composition and biological activity with ethanolic propolis extracts.ESI-MS and spectrophotometric methods were used for qualitative and quantitative analyses, respectively.Antibacterial activity was evaluated by diffusion in agar.Cytotoxicity was tested by MTT assay using tumor cell lines.The oil is able to extract bioactive compounds from propolis.Further studies are needed to improve extraction efficiency and to characterize the active components.

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