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The herpesvir us of sheep pulmonary adenomatosis

1979; Elsevier BV; Volume: 2; Issue: 2-3 Linguagem: Inglês

10.1016/0147-9571(79)90019-5

1878-1667

William B. Martin, K.W. Angus, GEORGE W. ROBINSON, Frank Scott,

Milk Quality and Mastitis in Dairy Cows

Abstract Sheep pulmonary adenomatosis is a contagious tumour of the lungs, which was first recognised in South Africa. The disease has now been reported in sheep from many parts of the world, affecting a wide variety of breeds and both sexes. Mortality may be heavy when the infection is introduced into flocks. Clinical signs are mainly those of chronic respiratory disease. Affected areas of lung are solid, enlarged and often light grey. On microscopic examination the main change in the tumour areas is that the alveoli are lined with cuboidal or columnar cells. A herpesvirus has been isolated from these tumours in sheep from four countries. No antigenic relationship to other herpesviruses is known. The weight of experimental evidence indicates that this virus does not cause disease in small laboratory animals or produce pulmonary adenomatosis in sheep.