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Effect of Seromuscular Colocystoplasty Lined with Urothelium and Partial Detrusorectomy on a New Canine Model of Reduced Bladder Capacity

1995; Lippincott Williams & Wilkins; Volume: 154; Issue: 2 Linguagem: Inglês

10.1016/s0022-5347(01)67199-4

1527-3792

Jorge Tapia Garibay, J. Carlos Manivel, Ricardo González,

Urinary Bladder and Prostate Research

No AccessJournal of UrologyAugmentation/Diversion1 Aug 1995Effect of Seromuscular Colocystoplasty Lined with Urothelium and Partial Detrusorectomy on a New Canine Model of Reduced Bladder Capacity Jorge Tapia Garibay, Juan Carlos Manivel, and Ricardo Gonzalez Jorge Tapia GaribayJorge Tapia Garibay More articles by this author , Juan Carlos ManivelJuan Carlos Manivel More articles by this author , and Ricardo GonzalezRicardo Gonzalez More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)67199-4AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail We developed a canine model of reduced bladder capacity by spraying talc on the outer surface of the detrusor after peeling the peritoneum from the bladder. This method was effective to reduce bladder capacity to almost a third of normal and this reduction persisted for the 6-month followup. On this model we performed detrusorectomy (auto-augmentation) and seromuscular colocystoplasty, and compared the results. Following detrusorectomy in talc bladder dogs bladder capacity failed to increase significantly at 3 months and 6 months. In contrast, seromuscular colocystoplasty caused a significant increase in bladder capacity in talc bladder dogs that was sustained for the 6-month followup. We also performed detrusorectomy in dogs with normal bladders and observed a progressive decrease in bladder capacity, which became significant at 6 months. Histology of the bladders after sacrifice revealed that talc induces a desmoplastic reaction around the detrusor that limits bladder distensibility and reduces its capacity. With detrusorectomy the perivesical fibrotic layer induced by talc and the detrusor were effectively removed but a thin layer of fibrosis developed between the bladder mucosa and the peritoneum that may account for the lack of improvement in bladder capacity. Identical observations were made after detrusorectomy in normal bladders. In contrast, following seromuscular colocystoplasty the bladder mucosa was adjacent to the submucosa of the colonic patch without fibrosis, a finding that may account for the restoration of bladder capacity. These experiments confirm previous experimental and clinical observations about seromuscular colocystoplasty, and suggest that it may result in better long-term results than simple auto-augmentation. References 1 : Seromuscular colocystoplasty lined with urothelium: experimental study. Urology1994; 44: 743. Google Scholar 2 : Agrandir la vessie. In: Chirurgie de la Vessie.. Paris: Masson1955: 200. Google Scholar 3 : A new technique for bladder reconstruction. Surg., Gynec. & Obst.1957; 105: 645. Medline, Google Scholar 4 : Autoaugmentation omentocystoplasty in a sheep model. Urology1994; 43: 888. Google Scholar 5 : Experiences with the detrusorectomy procedure. J. Urol., part 21990; 143: 331A. abstract 570. Google Scholar 6 : Bladder autoaugmentation: partial detrusor excision to augment the bladder without use of bowel. J. Urol.1989; 142: 1050. Link, Google Scholar 7 : Bladder autoaugmentation by vesicomyotomy in the pediatric neurogenic bladder. Urology1994; 44: 110. Google Scholar 8 : Early clinical experience with adult bladder autoaugmentation. J. Urol.1994; 152: 303. Abstract, Google Scholar 9 : Seromuscular enterocystoplasty in rats. J. Urol., part 21991; 146: 559. Abstract, Google Scholar 10 : Neourothelium in bladder augmentation. An experimental study in rats. Eur. Urol.1988; 14: 328. Google Scholar 11 : Seromuscular enterocystoplasty in dogs. J. Urol., part 21992; 147: 430A. abstract 870. Google Scholar 12 : Seromuscular enterocystoplasty in dogs. J. Urol., part 21990; 144: 454. Abstract, Google Scholar 13 : Seromuscular colocystoplasty lined with urothelium (SCLU). Experiment in 16 patients. Urology1995; 45: 124. Google Scholar Department of Urology, Children's Hospital of Michigan, Wayne State University, Detroit, Michigan, and Department of Laboratory Medicine and Pathology and Division of Pediatric Urology, Variety Club Children's Hospital, University of Minnesota, Minneapolis, Minnesota.© 1995 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byGonzález R, Ludwikowski B and Horst M (2009) Determinants of Success and Failure of Seromuscular Colocystoplasty Lined With UrotheliumJournal of Urology, VOL. 182, NO. 4S, (1781-1785), Online publication date: 1-Oct-2009.KÏBAR Y, TAHMAZ L, ÖNGÜRÜ Ö and DAYANÇ M (2018) PREVENTION OF COLONIC MUCOSAL REGROWTH AFTER SEROMUSCULAR ENTEROCYSTOPLASTYJournal of Urology, VOL. 165, NO. 6 Part 1, (2059-2062), Online publication date: 1-Jun-2001.AKTUĞ T, ZDEMİR T, AĞARTAN C, ÖZER E, OLGUNER M and AKGÜR F (2018) EXPERIMENTALLY PREFABRICATED BLADDERJournal of Urology, VOL. 165, NO. 6 Part 1, (2055-2058), Online publication date: 1-Jun-2001.DUEL B, GONZALEZ R and BARTHOLD J (2018) ALTERNATIVE TECHNIQUES FOR AUGMENTATION CYSTOPLASTYJournal of Urology, VOL. 159, NO. 3, (998-1005), Online publication date: 1-Mar-1998.Dewan P, Close C, Byard R, Ashwood P and Mitchell M (2018) Enteric Mucosal Regrowth After Bladder Augmentation Using Demucosalized Gut SegmentsJournal of Urology, VOL. 158, NO. 3, (1141-1146), Online publication date: 1-Sep-1997.Vates T, Denes E, Rabah R, Shapiro E, Suzer O, Freedman A and Gonzalez R (2018) Methods to Enhance in Vivo Urothelial Growth on Seromuscular Colonic Segments in the DogJournal of Urology, VOL. 158, NO. 3, (1081-1085), Online publication date: 1-Sep-1997.Gonzalez R (2018) Re: Laparoscopic Laser Assisted Auto-Augmentation of the Pediatric Neurogenic Bladder Early Experience with Urodynamic FollowupJournal of Urology, VOL. 156, NO. 5, (1783-1783), Online publication date: 1-Nov-1996. Volume 154Issue 2August 1995Page: 903-906 Advertisement Copyright & Permissions© 1995 by American Urological Association, Inc.MetricsAuthor Information Jorge Tapia Garibay More articles by this author Juan Carlos Manivel More articles by this author Ricardo Gonzalez More articles by this author Expand All Advertisement PDF downloadLoading ...