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RANDOM COLONY SELECTION VERSUS COLONY MORPHOLOGY FOR DETECTION OF MULTIPLE PNEUMOCOCCAL SEROTYPES IN NASOPHARYNGEAL SWABS

2008; Lippincott Williams & Wilkins; Volume: 27; Issue: 2 Linguagem: Inglês

10.1097/inf.0b013e31815bb6c5

1532-0987

Kim M. Hare, Peter S Morris, Heidi Smith‐Vaughan, Amanda Leach,

Bacterial Infections and Vaccines

Detection of multiple serotype carriage is important in understanding pneumococcal epidemiology. We compared random selection of 4 pneumococcal colonies per swab with selection by colony morphology. Multiple serotypes were detected in 20% of 98 swabs; 14% by morphology and 17% by random selection. Selection by morphology was more efficient per colony, but underestimated the true rate of multiple carriage.