Plasma Lidocaine Levels Following Hematoma Block for Distal Radius Fractures
1989; Lippincott Williams & Wilkins; Volume: 3; Issue: 3 Linguagem: Inglês
10.1097/00005131-198909000-00001
ISSN1531-2291
AutoresRichard P. Meinig, Allen Quick Lynette Lobmeyer,
Tópico(s)Hemodynamic Monitoring and Therapy
ResumoVenous plasma levels of lidocaine were determined in 8 patients presenting to the emergency department with acute distal radius fractures and who had had anesthesia with fracture hematoma block. The block was performed in an aseptic fashion via a dorsal approach with a dose of 2.2–2.4 mg/kg of lidocaine without epinephrine. Onset of anesthesia was in <5 min which reduced pain from manipulation of the fracture to modest levels. Plasma lidocaine levels determined by gas chromatography-mass Spectrometry reflected rapid systemic absorption of lidocaine from the fracture hematoma. Maximum systemic concentrations were seen at 20–30 min and ranged from 100 to 1,100 ng/ml, well below the toxic threshold of 5,000 ng/ml.
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