Circadian rhythm of histamine in the pineal gland
1974; Elsevier BV; Volume: 14; Issue: 3 Linguagem: Inglês
10.1016/0024-3205(74)90368-3
ISSN1879-0631
AutoresM. Garbarg, Christian Julien, Jean‐Charles Schwartz,
Tópico(s)Olfactory and Sensory Function Studies
ResumoAbstract Histamine content in the rat pineal gland was found to be close to the mean brain level. It exhibited a diurnal fluctuation in phase with that reported for melatonin : there was an approximately two-fold increase at the beginning of the dark period. Depleting the noradrenaline stores by reserpine or 6-hydroxydopamine resulted in a decreased histamine level. Taken together, these results suggest that the circadian rhythm in pineal histamine is driven by sympathetic activity.
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