Citrate bridges between mineral platelets in bone
2014; National Academy of Sciences; Volume: 111; Issue: 14 Linguagem: Inglês
10.1073/pnas.1315080111
ISSN1091-6490
AutoresErika Davies, Karin H. Müller, Wai Ching Wong, Chris J. Pickard, David G. Reid, Jeremy N. Skepper, Melinda J. Duer,
Tópico(s)Hydrocarbon exploration and reservoir analysis
ResumoSignificance Bone contains ∼2% wt citrate; however, its role in bone remains a much-debated question. We propose a new structure for bone mineral in which citrate in hydrated layers forms bridges between mineral platelets, which can explain a number of observations at odds with previous models. The incorporation of citrate between mineral platelets can explain the flat, plate-like morphology of bone mineral platelets and may be important in controlling the crystallinity of bone mineral, which in turn, is highly relevant to the mechanical properties of bone.
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