Portal de Periódicos da CAPES

A facile synthesis of 2H-indazoles under neat conditions and further transformation into aza-γ-carboline alkaloid analogues in a tandem one-pot fashion

2014; Royal Society of Chemistry; Volume: 4; Issue: 65 Linguagem: Inglês

10.1039/c4ra06838f

2046-2069

Shinde Vidyacharan, A. Sagar, N. C. Chaitra, Duddu S. Sharada,

Catalytic C–H Functionalization Methods

We have described a facile, microwave-assisted, catalyst-free and solvent-free approach to 2H-indazoles and further developed a robust tandem one-pot metal-free strategy for C–C bond formation at the C-3 position of 2H-indazoles leading to a unique class of aza-γ-carboline alkaloid analogues. This straightforward expedient synthesis constitutes an interesting alternative to the existing conventional transition metal catalyzed reactions.