Acquired, Transient Factor X (Stuart Factor) Deficiency in a Patient with Mycoplasma Pneumonial Infection

1979; Wiley; Volume: 23; Issue: 4 Linguagem: Inglês

10.1111/j.1600-0609.1979.tb02859.x

ISSN

0036-553X

Autores

F. W. Peuscher, W.G. van Aken, Jan A. van Mourik, A. J. G. Swaak, L. H. Sie, L.W. Statius van Eps,

Tópico(s)

Coagulation, Bradykinin, Polyphosphates, and Angioedema

Resumo

A case of severe haemorrhagic diathesis due to acquired deficiency of factor X (both immunologically and in procoagulant activity) is presented. The clinical and serological features of this case indicated mycoplasma pneumonial infection. Factor X in the peripheral blood did not appear to be influenced by administration of vitamin K, prothrombin-complex concentrate, fresh plasma or fresh whole blood. Circulating inhibitors of blood coagulation were absent and systemic amyloidosis could not be demonstrated. After 20 d, factor X spontaneously returned to normal. In view of the absence of other known causes of factor X deficiency, a possible relationship with mycoplasma pneumonial infection is suggested.

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