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BIBTEX RIS

Epstein-Barr virus DNA associated with gastric adenocarcinoma and adjacent non-cancerous mucosa in patients from Manaus, Brazil

2012; Research Foundation of Ribeirão Preto; Volume: 11; Issue: 4 Linguagem: Inglês

10.4238/2012.october.15.3

ISSN

1676-5680

Autores

Priscila Ferreira de Aquino, Paulo C. Carvalho, Joel Fischer, Antônia Queiroz Lima de Souza, Joaquim Viana, Sidney Raimundo Silva Chalub, Afonso Duarte Leão de Souza, M.G.C. Carvalho,

Tópico(s)

Genetics and Neurodevelopmental Disorders

Resumo

Gastric cancer is one of most frequent causes of death in Brazil.The city of Manaus has one of the highest incidences of this disease in Brazil.The Epstein-Barr virus (EBV) is a ubiquitous herpesvirus that is classified as a group 1 carcinogen by the International Agency for Research on Cancer.We obtained biopsies from 6 control subjects and 10 patients with gastric carcinomas living in Manaus.In the patients, the samples were taken from tumors and from adjacent non-cancerous mucosa.These samples were screened for EBV DNA by PCR to amplify the 288-bp fragments from the Bam M region.The ©FUNPEC-RP www.funpecrp.com.br

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