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Germline‐sequence variants S836S and L769L in the RE arranged during Transfection (RET) proto‐oncogene are not associated with predisposition to sporadic medullary carcinoma in the French population

2004; Wiley; Volume: 65; Issue: 2 Linguagem: Inglês

10.1111/j.0009-9163.2004.00172.x

1399-0004

Izabel Bérard, Jean Louis Kraimps, Frédérique Savagner, A. Murat, Karine Renaudin, P. Nicolli‐Sire, Gérald Bertrand, Jean-Pierre Moisan, Stéphane Bézieau,

Genomic variations and chromosomal abnormalities

Clinical GeneticsVolume 65, Issue 2 p. 150-152 Germline-sequence variants S836S and L769L in the RE arranged during Transfection (RET) proto-oncogene are not associated with predisposition to sporadic medullary carcinoma in the French population I. Berard, I. BerardSearch for more papers by this authorJ.-L. Kraimps, J.-L. KraimpsSearch for more papers by this authorF. Savagner, F. SavagnerSearch for more papers by this authorA. Murat, A. MuratSearch for more papers by this authorK. Renaudin, K. RenaudinSearch for more papers by this authorP. Nicolli-Sire, P. Nicolli-SireSearch for more papers by this authorG. Bertrand, G. BertrandSearch for more papers by this authorJ.-P. Moisan, J.-P. MoisanSearch for more papers by this authorS. Bezieau, Corresponding Author S. Bezieau S. Bezieau Faculté de Médecine Laboratoire d'Etude du Polymorphisme de l'ADN 1 rue Gaston Veil, BP53508, 44035 Nantes Cedex 01 France Tel.: +33 2 40 08 40 20 Fax: +33 2 40 08 40 20 E-mail: [email protected]Search for more papers by this author I. Berard, I. BerardSearch for more papers by this authorJ.-L. Kraimps, J.-L. KraimpsSearch for more papers by this authorF. Savagner, F. SavagnerSearch for more papers by this authorA. Murat, A. MuratSearch for more papers by this authorK. Renaudin, K. RenaudinSearch for more papers by this authorP. Nicolli-Sire, P. Nicolli-SireSearch for more papers by this authorG. Bertrand, G. BertrandSearch for more papers by this authorJ.-P. Moisan, J.-P. MoisanSearch for more papers by this authorS. Bezieau, Corresponding Author S. Bezieau S. Bezieau Faculté de Médecine Laboratoire d'Etude du Polymorphisme de l'ADN 1 rue Gaston Veil, BP53508, 44035 Nantes Cedex 01 France Tel.: +33 2 40 08 40 20 Fax: +33 2 40 08 40 20 E-mail: [email protected]Search for more papers by this author First published: 29 January 2004 https://doi.org/10.1111/j.0009-9163.2004.00172.xCitations: 22Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 Eng C. RET proto-oncogene in the development of human cancer. J Clin Oncol 1999: 17: 380–393. 2 Gimm O, Neuberg DS, Marsh DJ et al. Over-representation of a germline RET sequence variant in patients with sporadic medullary thyroid carcinoma and somatic RET codon 918 mutation. Oncogene 1999: 18: 1369–1373. 3 Ruiz A, Antinolo G, Fernandez RM, Eng C, Marcos I, Borrego S. Germline sequence variant S836S in the RET proto-oncogene is associated with low level predisposition to sporadic medullary thyroid carcinoma in the Spanish population. Clin Endocrinol (Oxf) 2001: 55: 399–402. 4 Borrego S, Wright FA, Fernandez RM et al. Afounding locus within the RET proto-oncogene may account for a large proportion of apparently sporadic Hirschsprung's disease and a subset of cases of sporadic medullary thyroid carcinoma. Am J Hum Genet 2003: 72: 88–100. 5 Patocs A, Valkusz Z, Igaz P et al. Segregation of the V804L mutation and S836S polymorphism of exon 14 of the RET gene in an extended kindred with familial medullary thyroid cancer. Clin Genet 2003: 63: 219–223. 6 Wiench M, Wygoda Z, Gubala E et al. Estimation of risk of inherited medullary thyroid carcinoma in apparent sporadic patients. J Clin Oncol 2001: 19: 1374–1380. 7 Ferrie RM, Schwarz MJ, Robertson NH et al. Development, multiplexing and application of ARMS tests for common mutations in the CFTR gene. Am J Hum Genet 1992: 51: 251–262. 8 Zedenius J, Wallin G, Hamberger B, Nordenskjold M, Weber G, Larsson C. Somatic and MEN 2A de novo mutations identified in the RET proto-oncogene by screening of sporadic MTCs. Hum Mol Genet 1994: 3: 1259–1262. Citing Literature Volume65, Issue2February 2004Pages 150-152 ReferencesRelatedInformation