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TRANSLATION OF THE GENETIC MESSAGE, III. FORMYLMETHIONINE AS INITIATOR OF PROTEINS PROGRAMED BY POLYCISTRONIC MESSENGER RNA

1967; National Academy of Sciences; Volume: 57; Issue: 3 Linguagem: Inglês

10.1073/pnas.57.3.729

1091-6490

Eladio Viñuela, Margarita Salas, Severo Ochoa,

Animal Genetics and Reproduction

The sequential production of cell types during neural development is controlled by temporal identity transcription factors, and heterochronic expression of these factors in progenitors reprograms developmental potential and promotes the ...Temporal identity factors are sufficient to reprogram developmental competence of neural progenitors and shift cell fate output, but whether they can also reprogram the identity of terminally differentiated cells is unknown. To address this question, we ...