Artigo Acesso aberto Produção Nacional Revisado por pares

A frequência do HPV na mucosa oral normal de indivíduos sadios por meio da PCR

2010; Elsevier BV; Volume: 76; Issue: 1 Linguagem: Inglês

10.1590/s1808-86942010000100013

ISSN

1808-8694

Autores

David Esquenazi, Ivo Bussoloti Filho, María da Gloria Carvalho, Fernando Souza de Barros,

Tópico(s)

Oral Health Pathology and Treatment

Resumo

The human papillomavirus (HPV) is a DNA virus, which belongs to papillomaviridae family, being of low and high risk, which infect the skin and mucous membranes and can induce benign and malign tumor formation. In the oral mucosa they have been associated with oral papilloma, focal epithelial hyperplasia, leucoplakia and oral neoplasia.to study the frequency of HPV finding in oral mucosa of normal people.Prospective study, cross-sectional cohort. One hundred volunteers, young adults, healthy, aged between 20 and 31 years, university students with no history, no complains, without oral or oropharyngeal lesions. They were submitted to a questionnaire with questions regarding HPV infection epidemiology. The samples were harvested by brushing and analyzed by PCR.The results were negative for HPV in all samples.It seems we had high social and economical class individuals, with nutrition rich in carotenoyds and vitamin C, low smoking and alcohol consumption and heterosexual habits with predominant monogamy and regular use of condoms.

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