
A frequência do HPV na mucosa oral normal de indivíduos sadios por meio da PCR
2010; Elsevier BV; Volume: 76; Issue: 1 Linguagem: Inglês
10.1590/s1808-86942010000100013
ISSN1808-8694
AutoresDavid Esquenazi, Ivo Bussoloti Filho, María da Gloria Carvalho, Fernando Souza de Barros,
Tópico(s)Oral Health Pathology and Treatment
ResumoThe human papillomavirus (HPV) is a DNA virus, which belongs to papillomaviridae family, being of low and high risk, which infect the skin and mucous membranes and can induce benign and malign tumor formation. In the oral mucosa they have been associated with oral papilloma, focal epithelial hyperplasia, leucoplakia and oral neoplasia.to study the frequency of HPV finding in oral mucosa of normal people.Prospective study, cross-sectional cohort. One hundred volunteers, young adults, healthy, aged between 20 and 31 years, university students with no history, no complains, without oral or oropharyngeal lesions. They were submitted to a questionnaire with questions regarding HPV infection epidemiology. The samples were harvested by brushing and analyzed by PCR.The results were negative for HPV in all samples.It seems we had high social and economical class individuals, with nutrition rich in carotenoyds and vitamin C, low smoking and alcohol consumption and heterosexual habits with predominant monogamy and regular use of condoms.
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