γ-alkylation of α,β-unsaturated ketones: α'-phenylsulfonyl groups as regioselective control elements
1985; Elsevier BV; Volume: 26; Issue: 2 Linguagem: Inglês
10.1016/s0040-4039(00)61871-3
ISSN1873-3581
AutoresPeter T. Lansbury, Gregory E. Bebernitz, Susan C. Maynard, Ciro J. Spagnuolo,
Tópico(s)Chemical Synthesis and Reactions
ResumoThe α'-phenylsulfonyl derivative of E-3-penten-2-one (3) undergoes predominant γ-alkylation with a variety of alkyl iodides when first converted into a trilithiated intermediate with excess lithium diisopropylamide in tetrahydrofuran-hexane.
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