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Ganciclovir and the treatment of Epstein‐Barr virus hepatitis

2006; Wiley; Volume: 21; Issue: 11 Linguagem: Inglês

10.1111/j.1440-1746.2006.03257.x

1440-1746

Leon A. Adams, Bastiaan DeBoer, Gary P. Jeffrey, Richard Marley, George Garas,

Herpesvirus Infections and Treatments

Abstract Epstein‐Barr virus (EBV) is part of the herpesvirus family that infects up to 90% of the population. Initial infection is often subclincal in children but will generally result in symptomatic infectious mononucleosis in adolescents and adults. Ganciclovir has been utilized in immunocompromised patients with EBV encephalitis and post‐liver transplant for EBV fulminant hepatitis. Herein, the successful use of ganciclovir in two immunocompetent patients with severe EBV hepatitis is reported.