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Artigo Acesso aberto Produção Nacional Revisado por pares
BIBTEX RIS

Measles antibody prevalence after mass immunization campaign in Niterói, State of Rio de Janeiro, Brazil

1996; UNIVERSIDADE DE SÃO PAULO; Volume: 38; Issue: 5 Linguagem: Inglês

10.1590/s0036-46651996000500006

ISSN

1678-9946

Autores

Solange Artimos de Oliveira, Marilda Mendonça Siqueira, G.F. Mann, Antônio José Leal Costa, Maria Teresa C.N. Almeida, Mônica S. Stavola, Hugo Tomasini, Jussara Pereira do Nascimento,

Tópico(s)

Vaccine Coverage and Hesitancy

Resumo

Three months after a mass vaccination campaign (coverage: 100%) against measles a random seroepidemiological survey was carried out in students aged 1 to 19 years old in the Municipality of Niterói, State of Rio de Janeiro. Blood samples were tested for measles antibodies by enzyme immunosorbent assay (EIA) and negative cases were tested again using hemagglutination inhibition (HI) and plaque reduction neutralization (PRN). Of the 798 samples tested by EIA, 718 (90.2%) were positive for measles antibodies. PRN test was more sensitive than EIA and HI in detecting measles specific antibodies. The total antibody prevalence increased from 90.2% to 93.2% when HI was employed in EIA negative specimens and to 98.9% when PRN was used. After the mass vaccination campaign a marked decrease in measles incidence was observed in the municipality studied, showing the effectiveness of the strategy used for measles control in developing countries.

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