TRANSMISSION OF STREPTOMYCIN-RESISTANT TUBERCLE BACILLI IN MAN
1949; American Medical Association; Volume: 140; Issue: 16 Linguagem: Inglês
10.1001/jama.1949.82900510004006b
ISSN1538-3598
Autores Tópico(s)Tuberculosis Research and Epidemiology
ResumoA new and potentially serious problem of public health has been anticipated in view of the steadily increasing number of cases of pulmonary tuberculosis in which patients, after treatment with streptomycin, remain sputum positive with the tubercle bacilli Lightly resistant to streptomycin. We have learned by animal experimentation that such resistance is probably permanent and that a tuberculous infection resistant to subsequent streptomycin therapy can be transmitted from one animal to another. Finally, there is growing evidence to indicate not only that streptomycin is ineffective in combating such an infection but that its use may actually accelerate the tuberculous process. The following case report indicates that such transmission of streptomycin-resistant tuberculosis can occur in man. REPORT OF CASE A woman aged 36, a lieutenant of the Navy Nurse Corps, was admitted to the sick list on June 28, 1947 at the United States Naval Hospital, Corona, Calif. Her known exposure
Referência(s)