Artigo Revisado por pares

ARYLPYRIDINES: PART II. REACTION OF PHENYLLITHIUM WITH 3-METHOXY- AND 3-AMINO-PYRIDINE

1960; NRC Research Press; Volume: 38; Issue: 9 Linguagem: Inglês

10.1139/v60-203

ISSN

1480-3291

Autores

R. A. Abramovitch, Albert D. Notation,

Tópico(s)

Synthesis and Reactions of Organic Compounds

Resumo

Phenyllithium has been shown to react with 3-methoxy- and 3-amino-pyridine to give exclusively 3-methoxy-2-phenylpyridine and 3-amino-2-phenylpyridine respectively. The orientation of the products has been established unambiguously. None of the 2,5-isomer was detected in either case. An explanation for this unique orientation is suggested.

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