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Clinical comparison of D-Tubocurarine and pancuronium: Dosage schedule based on lean body mass

1973; Springer Nature; Volume: 20; Issue: 2 Linguagem: Inglês

10.1007/bf03027210

0008-2856

E. Nickorick, F. B. Reynolds,

Nausea and vomiting management

PANCURONIUM BROMIDE, a non-depolarizing neuromuscular blocking agent, was first reported in use in anaesthetized patients in 1967 by Baird and Reid. 1 Pharmacological properties were described by Buckett and associates in 1968. 2Pancuronium is a bisquaternary amino steroid said to have approximately five times the potency of d-tubocurarine in man.It is of particular interest to note that this is the first steroid compound with muscle relaxant properties to be used in clinical practice.