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Membranoproliferative Glomerulonephritis Associated with Hepatitis C Virus Infection

1993; Massachusetts Medical Society; Volume: 328; Issue: 7 Linguagem: Inglês

10.1056/nejm199302183280703

1533-4406

Richard J. Johnson, David R. Gretch, Hideaki Yamabe, Jaime Hart, Carlos E. Bacchi, Peter Hartwell, William G. Couser, Lawrence Corey, Mark H. Wener, Charles E. Alpers, Richard A. Willson,

Chronic Lymphocytic Leukemia Research

Hepatitis C virus (HCV) infection causes both acute and chronic liver disease and is also associated with mixed cryoglobulinemia. Whether HCV is also associated with renal disease, as is the hepatitis B virus, is not known. We describe the clinical, pathologic, virologic, and immunologic features of eight patients with HCV infection who were referred to nephrologists for glomerulonephritis. Four patients were treated with interferon alfa.