Artigo Acesso aberto Revisado por pares

Dendritic epidermal T cells: Activation requirements and phenotypic characterization of proliferating cells

1989; Elsevier BV; Volume: 92; Issue: 5 Linguagem: Inglês

10.1016/0022-202x(89)90197-8

ISSN

1523-1747

Autores

Erwin Tschachler, Georg Steiner, Hidekazu Yamada, Adelheid Elbe, Klaus Wolff, Georg Stingl,

Tópico(s)

Immune Cell Function and Interaction

Resumo

Dendritic epidermal T cells (DETC) are CD45+, Thy-l+, CD5-, CD8-, CD4murine lymphocytes that express surface-bound CD3 antigens associated with T cell receptor y/S heterodimers.Using epidermal cells greatly enriched for DETC and depleted of Langerhans cells, we found that DETC have growth requirements quite different from those of accessory cell-depleted lymph node and splenic T cells.

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