Spherocyte shape transformation and release of tubular nanovesicles in human erythrocytes
2003; Elsevier BV; Volume: 62; Issue: 2 Linguagem: Inglês
10.1016/j.bioelechem.2003.07.002
ISSN1878-562X
AutoresAleš Iglič, Peter Veranič, Kristijan Jezernik, Miha Fošnarič, Boris Kamin, Henry Hägerstrand, Veronika Kralj‐Iglič,
Tópico(s)Blood properties and coagulation
ResumoWe have studied dodecylmaltoside-induced echinocyte-spheroechincyte-spherocyte shape transformation and membrane vesiculation using transmission electron microscopy (TEM) on freeze-fracture replicas. It is indicated that spherical erythrocyte shape at higher dodecylmaltoside concentration is formed due to loss of membrane in the process where small, mostly tubular nanovesicles are released predominantly from the top of echinocyte and spheroechinocyte spicules.
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