Trauma and immune reactivity: Too much, or too little immune response?
2007; Elsevier BV; Volume: 38; Issue: 12 Linguagem: Inglês
10.1016/j.injury.2007.10.007
ISSN1879-0267
AutoresPeter V. Giannoudis, Hans‐Christoph Pape,
Tópico(s)Abdominal Trauma and Injuries
ResumoThe management of trauma has evolved significantly during the last few decades. The continuous improvements made in all aspects of care (rescue time, resuscitation, diagnostics, implant technology, critical care medicine, pharmacological agents, etc.) have made essential contributions to the number of patients who survive trauma. 1 ACS ACoS. ATLS, Advanced Trauma Life Support. Instructor course manual; 1997. Google Scholar , 3 Athanassiadi K. Gerazounis M. Repair of postintubation tracheoesophageal fistula in polytrauma patients. Injury. 2005; 36: 897-899 Abstract Full Text Full Text PDF Scopus (7) Google Scholar , 5 Bose D. Tejwani N.C. Evolving trends in the care of polytrauma patients. Injury. 2006; 37: 20-28 Abstract Full Text Full Text PDF PubMed Scopus (46) Google Scholar , 6 Brooks A.J. Sperry D. Riley B. Girling K.J. Improving performance in the management of severely injured patients in critical care. Injury. 2005; 36: 310-316 Abstract Full Text Full Text PDF Scopus (14) Google Scholar , 8 Castelli P. Caronno R. Piffaretti G. Tozzi M. Lagana D. Carrafiello G. Cuffari S. Endovascular repair of traumatic injuries of the subclavian and axillary arteries. Injury. 2005; 36: 778-782 Abstract Full Text Full Text PDF PubMed Scopus (74) Google Scholar , 9 Chawda M.N. Hildebrand F. Pape H.C. Giannoudis P.V. Predicting outcome after multiple trauma: which scoring system?. Injury. 2004; 35: 347-358 Abstract Full Text Full Text PDF Scopus (203) Google Scholar , 10 Elder G.M. Harvey E.J. Vaidya R. Guy P. Meek R.N. Aebi M. The effectiveness of orthopaedic trauma theatres in decreasing morbidity and mortality: A study of 701 displaced subcapital hip fractures in two trauma centres. Injury. 2005; 36: 1060-1066 Abstract Full Text Full Text PDF Scopus (43) Google Scholar , 12 Franklin G.A. Casos S.R. Current advances in the surgical approach to abdominal trauma. Injury. 2006; 37: 1143-1156 Abstract Full Text Full Text PDF Scopus (59) Google Scholar , 14 Giannoudis P.V. Surgical priorities in damage control in polytrauma. J Bone Joint Surg Br. 2003; 85: 478-483 Crossref PubMed Scopus (151) Google Scholar , 17 Giannoudis P.V. Pape H.C. Damage control orthopaedics in unstable pelvic ring injuries. Injury. 2004; 35: 671-677 Abstract Full Text Full Text PDF PubMed Scopus (211) Google Scholar , 19 Giannoudis P.V. Tzioupis C. Pape H.C. Fat embolism: the reaming controversy. Injury. 2006; 37: S50-S58 Abstract Full Text PDF Scopus (77) Google Scholar , 20 Grotz M.R.W. Allami M.K. Harwood P. Pape H.C. Krettek C. Giannoudis P.V. Open pelvic fractures: Epidemiology, current concepts of management and outcome. Injury. 2005; 36: 1-13 Abstract Full Text Full Text PDF Scopus (207) Google Scholar , 21 Grotz M.R. Giannoudis P.V. Pape H.C. et al. Traumatic brain injury and stabilisation of long bone fractures: an update. Injury. 2004; 35: 1077-1086 Abstract Full Text Full Text PDF Scopus (24) Google Scholar , 22 Grotz M. Gummerson N. Gänsslen A. et al. Staged management and outcome of combined pelvic and liver trauma: an International experience of the Lethal Duet. Injury. 2006; 37: 642-651 Abstract Full Text Full Text PDF Scopus (25) Google Scholar , 27 Hildebrand F. Giannoudis P.V. Griensven M.V. Zelle B. Ulmer B. Krettek C. Bellamy M.C. Pape H.-C. Management of polytraumatized patients with associated blunt chest trauma: A comparison of two European countries. Injury. 2005; 36: 293-302 Abstract Full Text Full Text PDF Scopus (66) Google Scholar , 38 Pape H.C. Giannoudis P. Krettek C. The timing of fracture treatment in polytrauma patients: relevance of damage control orthopedic surgery. Am J Surg. 2002; 183: 622-629 Abstract Full Text Full Text PDF PubMed Scopus (298) Google Scholar , 41 Renaldo N. Egol K. Damage-control orthopedics: evolution and practical applications. Am J Orthop. 2006; 35 (Discussion 91): 285-291 Google Scholar , 48 Susmallian S. Ezri T. Elis M. Dayan K. Charuzi I. Muggia-Sullam M. Gluteal stab wound is a frequent and potentially dangerous injury. Injury. 2005; 36: 148-150 Abstract Full Text Full Text PDF Scopus (11) Google Scholar , 50 Willis C.D. Cameron P.A. Bernard S.A. Fitzgerald M. Cardiopulmonary resuscitation after traumatic cardiac arrest is not always futile. Injury. 2006; 37: 448-454 Abstract Full Text Full Text PDF PubMed Scopus (73) Google Scholar , 51 Willschke H. Bosenberg A. Marhofer P. et al. Ultrasonographic-guided ilioinguinal/iliohypogastric nerve block in pediatric anesthesia: what is the optimal volume?. Anesth Analg. 2006; 102: 1680-1684 Crossref PubMed Scopus (153) Google Scholar , 52 Zander J. Polytrauma as a cause of multiple organ failure. Anasth Intensivther Notfallmed. 1989; 24: 216-220 Crossref Scopus (4) Google Scholar Most importantly though, the exceptional advances of the medical, surgical and basic sciences have led to an increased understanding of the pathophysiological events governing the host response to both surgical and accidental injury. 7 Brown J.M. Grosso M.A. Harken A.H. Cytokines, sepsis and the surgeon. Surg Gynecol Obstet. 1989; 169: 568-575 PubMed Google Scholar , 15 Giannoudis P.V. Dinopoulos H. Chalidis B. Hall G.M. Surgical stress response. Injury. 2006; 37: S3-S9 Abstract Full Text PDF PubMed Scopus (111) Google Scholar , 17 Giannoudis P.V. Pape H.C. Damage control orthopaedics in unstable pelvic ring injuries. Injury. 2004; 35: 671-677 Abstract Full Text Full Text PDF PubMed Scopus (211) Google Scholar , 24 Harris B.H. Gelfand J.A. The immune response to trauma. Semin Pediatr Surg. 1995; 4: 77-82 PubMed Google Scholar , 37 Osborn L. Leukocyte adhesion to endothelium in inflammation. Cell. 1990; 62: 3-6 Abstract Full Text PDF PubMed Scopus (863) Google Scholar , 39 Pape H.-C. Hildebrand F. Krettek C. Green J. Giannoudis P.V. Experimental background-review of animal studies. Injury. 2006; 37: S25-S38 Abstract Full Text PDF Scopus (14) Google Scholar , 45 Smith R.M. Giannoudis P.V. Trauma and the immune response. J R Soc Med. 1998; 91: 417-420 Google Scholar It is now becoming clear that the problem of managing patients with multiple injuries has shifted from early and effective resuscitation to the treatment of the host response to injury. 2 Alpantaki K. Tsiridis E. Pape H.C. Giannoudis P.V. Application of clinical proteomics in diagnosis and management of trauma patients. Injury. 2007; 38: 263-271 Abstract Full Text Full Text PDF Scopus (19) Google Scholar , 15 Giannoudis P.V. Dinopoulos H. Chalidis B. Hall G.M. Surgical stress response. Injury. 2006; 37: S3-S9 Abstract Full Text PDF PubMed Scopus (111) Google Scholar , 16 Giannoudis P.V. Fogerty S. Initial care of the severely injured patient: predicting morbidity from sub-clinical findings and clinical proteomics. Injury. 2007; 38: 261-262 Abstract Full Text Full Text PDF Scopus (7) Google Scholar , 31 Keel M. Trentz O. Pathophysiology of polytrauma. Injury. 2005; 36: 691-709 Abstract Full Text Full Text PDF PubMed Scopus (691) Google Scholar
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