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Implementation of One Step Nucleic acid Amplification (OSNA) for Intra-operative assessment of sentinel lymph nodes in a DGH

2012; Elsevier BV; Volume: 38; Issue: 5 Linguagem: Inglês

10.1016/j.ejso.2012.02.110

1532-2157

Mohd Iqbal, Ali Jibran Mecci, Lisa Whisker, Michael A. Parkes, Adrian Smith, Farah Sandhu, Simon Harries, Dayalan Clarke, Lucie Jones,

Nonmelanoma Skin Cancer Studies

Background: Intra-operative assessment of the sentinel lymph node (SLN) saves a second operation for women with axillary metastatic disease. The techniques used for intra-operative assessment of the SLN include frozen section, touch imprint cytology (TIC) and more recently molecular biology assays. We have recently introduced molecular assay (OSNA) for the intra-operative assessment of the sentinel node in our institution. The aim of this study was to audit our early results with OSNA.