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Impact of duration of rupture of membranes on outcomes of premature infants

2014; Springer Nature; Volume: 34; Issue: 9 Linguagem: Inglês

10.1038/jp.2014.73

1476-5543

M. Whit Walker, Amy H. Picklesimer, Reese H. Clark, Alan R. Spitzer, Thomas J. Garite,

Neonatal and Maternal Infections

The primary aim of the study was to determine how the risk of adverse outcomes was related to the duration of the latency period and gestational age at birth following preterm premature rupture of the fetal membranes (PPROM).Retrospective review of infants discharged from 330 neonatal intensive care units. We defined four subgroups based on gestational age: 23 to 25, 26 to 28, 29 to 31 and 32 to 34 weeks. Each gestational age group was evaluated by duration of ROM: 28 days and compared with a referent group (PPROM of >24 h but 24 h. Compared with a reference group (PPROM of >24 h but 28 days was consistently associated with increased mortality and decreased likelihood of survival without morbidity in all gestational age subgroups.PPROM for >28 days is associated with an increased risk of death and morbidity.