
Mechanical and electrical properties of red blood cells using optical tweezers
2011; IOP Publishing; Volume: 13; Issue: 4 Linguagem: Inglês
10.1088/2040-8978/13/4/044012
ISSN2040-8986
AutoresAdriana Fontes, Mario Castro, M M Brandão, Heloise P. Fernandes, André A. de Thomaz, R.R. Huruta, L. Y. Pozzo, Luíz C. Barbosa, Fernando Ferreira Costa, Sara T.O. Saad, Carlos L. Cesar,
Tópico(s)Orbital Angular Momentum in Optics
ResumoOptical tweezers are a very sensitive tool, based on photon momentum transfer, for individual, cell by cell, manipulation and measurements, which can be applied to obtain important properties of erythrocytes for clinical and research purposes. Mechanical and electrical properties of erythrocytes are critical parameters for stored cells in transfusion centers, immunohematological tests performed in transfusional routines and in blood diseases. In this work, we showed methods, based on optical tweezers, to study red blood cells and applied them to measure apparent overall elasticity, apparent membrane viscosity, zeta potential, thickness of the double layer of electrical charges and adhesion in red blood cells.
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