Produção Nacional
Revisado por pares
Efetividade da bupropiona no tratamento de pacientes tabagistas com doença cardiovascular
2007; Sociedade Brasileira de Cardiologia (SBC); Volume: 88; Issue: 4 Linguagem: Inglês
10.1590/s0066-782x2007000400012
ISSN1678-4170
AutoresJaqueline Schölz Issa, Glória Heloise Perez, J Diament, Angela Giuliana Zavattieri, Kátia Ulrich de Oliveira,
Tópico(s)Behavioral Health and Interventions
ResumoTo evaluate the effectiveness of and tolerability to sustained-release bupropion, in smokers with cardiovascular diseases treated in a smoking cessation service, as well as to investigate variables predictive of success or failure in smoking cessation.Sustained-release bupropion was prescribed to 100 current smokers with cardiovascular disease for 12 weeks. Patients were followed for 52 week. The variables studied were gender, age, number of cigarettes, exhaled carbon monoxide, nicotine dependence (Fagerstrom Tolerance Questionnaire), depression (Beck Depression Inventory), anxiety (State-Trait Anxiety Inventory), alcohol consumption (Alcohol Use Disorders Identification Test), number of diagnoses other than smoking, adverse events, and use of medications concomitantly with sustained-release bupropion.Abstinence rate was 50% at week 12 and 25% at week 52. The logistic regression analysis showed that ageing was positively associated with success, whereas the worsening of the condition, as verified by the presence of a higher number of other health conditions associated with smoking, was negatively associated with success.We conclude that the prescription of bupropion for smokers with cardiovascular diseases proved to be safe and effective, especially during the treatment period (week 12).
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