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Muscle Differentiation: Which myogenic factors make muscle?

1994; Elsevier BV; Volume: 4; Issue: 1 Linguagem: Inglês

10.1016/s0960-9822(00)00014-2

1879-0445

Margaret Buckingham,

Genetic Neurodegenerative Diseases

Mice lacking myogenin have little skeletal muscle as fibres fail to differentiate. Lack of both MyoD and myf-5 results in no skeletal muscle and apparently no myoblasts, suggesting that these factors act earlier in muscle development.