Artigo Produção Nacional Revisado por pares

Cancer chemopreventive effects of a Brazilian folk medicine, Juca, on in vivo two-stage skin carcinogenesis

2002; Elsevier BV; Volume: 81; Issue: 1 Linguagem: Inglês

10.1016/s0378-8741(02)00047-8

ISSN

1872-7573

Autores

Eliane Shizuka Nakamura, Fumiya Kurosaki, Munehisa Arisawa, Teruo Mukainaka, Junko Takayasu, Masato Okuda, Harukuni Tokuda, Hoyoku Nishino, Floriano Pastore,

Tópico(s)

Effects of Radiation Exposure

Resumo

Gallic acid (1) and methyl gallate (2) were isolated from Juca, a Brazilian folk medicine, fruits of Caesalpinia ferrea Mart (Leguminosae), decreased significantly the average number of papillomas per mouse in the experiment of the promoting effects of 12-O-tetra- decanoylphorbol-13-acetate (TPA) on skin tumor formation in mice initiated with 7,12-dimethylbenz[a]anthracene (DMBA).

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