Non‐neutralizing anti‐FVIII antibodies: different binding specificity to different recombinant FVIII concentrates
2008; Wiley; Volume: 15; Issue: 1 Linguagem: Italiano
10.1111/j.1365-2516.2008.01909.x
ISSN1365-2516
AutoresAnne-Marie Vincent, David Lillicrap, A. Boulanger, Courtney Meilleur, Claudine Amesse, Jean St‐Louis, Georges‐Étienne Rivard,
Tópico(s)Blood Coagulation and Thrombosis Mechanisms
ResumoHaemophiliaVolume 15, Issue 1 p. 374-376 Non-neutralizing anti-FVIII antibodies: different binding specificity to different recombinant FVIII concentrates A. M. VINCENT, A. M. VINCENT Centre Hospitalier Universitaire Sainte-Justine, MontréalSearch for more papers by this authorD. LILLICRAP, D. LILLICRAP Richardson Laboratory, Queen's University, KingstonSearch for more papers by this authorA. BOULANGER, A. BOULANGER Centre Hospitalier Universitaire Sainte-Justine, MontréalSearch for more papers by this authorC. MEILLEUR, C. MEILLEUR Centre Hospitalier Universitaire Sainte-Justine, MontréalSearch for more papers by this authorC. AMESSE, C. AMESSE Centre Hospitalier Universitaire Sainte-Justine, MontréalSearch for more papers by this authorJ. ST-LOUIS, J. ST-LOUIS Hôpital Maisonneuve-Rosemont, Montréal, CanadaSearch for more papers by this authorG. E. RIVARD, G. E. RIVARD Centre Hospitalier Universitaire Sainte-Justine, MontréalSearch for more papers by this author A. M. VINCENT, A. M. VINCENT Centre Hospitalier Universitaire Sainte-Justine, MontréalSearch for more papers by this authorD. LILLICRAP, D. LILLICRAP Richardson Laboratory, Queen's University, KingstonSearch for more papers by this authorA. BOULANGER, A. BOULANGER Centre Hospitalier Universitaire Sainte-Justine, MontréalSearch for more papers by this authorC. MEILLEUR, C. MEILLEUR Centre Hospitalier Universitaire Sainte-Justine, MontréalSearch for more papers by this authorC. AMESSE, C. AMESSE Centre Hospitalier Universitaire Sainte-Justine, MontréalSearch for more papers by this authorJ. ST-LOUIS, J. ST-LOUIS Hôpital Maisonneuve-Rosemont, Montréal, CanadaSearch for more papers by this authorG. E. RIVARD, G. E. RIVARD Centre Hospitalier Universitaire Sainte-Justine, MontréalSearch for more papers by this author First published: 15 January 2009 https://doi.org/10.1111/j.1365-2516.2008.01909.xCitations: 13 Georges E. Rivard, MD, Division of Hematology-Oncology, Centre Hospitalier Universitaire Sainte-Justine, Room A474, 3175 Chemin Côte-Ste-Catherine, Montréal, QC, Canada H3T 1C5.Tel.: 514 345 4931, ext. 6717; fax: 514 345 4884;e-mail: [email protected] Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 Lavigne-Lissalde G, Lacroix-Desmazes S, Wootla B et al. Molecular characterization of human B domain-specific anti-factor VIII monoclonal antibodies generated in transgenic mice. Thromb Haemost 2007; 98: 138– 47. 2 Towfighi F, Gharagozlou S, Sharifian RA et al. Comparative measurement of anti-factor VIII antibody by Bethesda assay and ELISA reveals restrictive isotype profile and epitope specificity. Acta Haematol 2005; 114: 84– 90. 3 Sahud MA, Pratt KP, Zhukov O, Qu K, Thompson AR. ELISA system for detection of immune response to FVIII: a study of 246 samples and correlation with the Bethesda assay. Haemophilia 2007; 13: 317– 22. 4 Ling M, Duncan EM, Rodgers SE, Street AM, Lloyd JV. Low detection rate of antibodies to non-functional epitopes of factor VIII in patients with hemophilia A and negative for inhibitors by Bethesda assay. J Thromb Haemost 2003; 1: 2548– 53. 5 Astermark J, Voorberg J, Lenk H et al. Impact of inhibitor epitope profile on the neutralizing effect against plasma-derived and recombinant factor VIII concentrates in vitro. Haemophilia 2003; 9: 567– 72. Citing Literature Volume15, Issue1January 2009Pages 374-376 ReferencesRelatedInformation
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