Antimicrobial and cytotoxic activities of Laportea crenulata

2008; Elsevier BV; Volume: 79; Issue: 7-8 Linguagem: Inglês

10.1016/j.fitote.2008.04.007

ISSN

1873-6971

Autores

M. Mukhlesur Rahman, Alam Khan, Mohammad Rashedul Haque, M. Motiur Rahman,

Tópico(s)

Essential Oils and Antimicrobial Activity

Resumo

Crude extracts and 2α,3β,21β,24β,28-pentahydroxy-olean-12-ene (1) obtained from the root of Laportea crenulata exhibited remarkable antibacterial activities against both Gram (+) and Gram (−) bacteria. The antifungal activities of crude extracts and compound (1) were also determined. The cytotoxic activities of crude extracts and compound (1) were observed by brine shrimp bioassay and LC50 value of the compound (1) was found to be 27.54 µg/ml.

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