Neopentylglycolborylation of Aryl Mesylates and Tosylates Catalyzed by Ni-Based Mixed-Ligand Systems Activated with Zn
2010; American Chemical Society; Volume: 132; Issue: 6 Linguagem: Inglês
10.1021/ja910808x
ISSN1943-2984
AutoresDaniela A. Wilson, Christopher J. Wilson, Costel Moldoveanu, Ana-Maria Resmeriță, Patrick Corcoran, Lisa M. Hoang, Brad M. Rosen, Virgil Percec,
Tópico(s)Peptidase Inhibition and Analysis
ResumoThe mixed-ligand system NiCl2(dppp)/dppf is shown to be an effective catalyst for the neopentylglycolborylation of ortho-, meta-, and para-substituted electron-rich and electron-deficient aryl mesylates and tosylates. The addition of Zn powder as a reductant dramatically increases the reaction yield and reduces the reaction time by more than an order of magnitude, providing complete conversion in 1−3 h.
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