SQ 26,180, a novel monobactam. II. Isolation, structure determination and synthesis.
1982; Springer Nature; Volume: 35; Issue: 2 Linguagem: Inglês
10.7164/antibiotics.35.189
ISSN1881-1469
AutoresW. Parker, William H. Koster, C. M. CIMARUSTI, David Floyd, Wen-Chih Liu, Marlene L. Rathnum,
Tópico(s)Chemical Synthesis and Analysis
ResumoA novel monocyclic β-lactam antibiotic SQ 26, 180 has been isolated from bacteria and the structure, (R)-3-acetylamino-3-methoxy-2-oxo-1-azetidinesulfonic acid was deduced from its spectroscopic properties. Structural confirmation and assignment of absolute configuration were made by synthesis from 6-aminopenicillanic acid.
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