The Impact of Prostate Biopsy and Periprostatic Nerve Block on Erectile and Voiding Function: A Prospective Study
2010; Lippincott Williams & Wilkins; Volume: 184; Issue: 4 Linguagem: Inglês
10.1016/j.juro.2010.06.021
ISSN1527-3792
AutoresTobias Klein, Rein Jueri Palisaar, Alexander Holz, Marko Brock, Joachim Noldus, Andreas Hinkel,
Tópico(s)Prostate Cancer Diagnosis and Treatment
ResumoNo AccessJournal of UrologyAdult Urology1 Oct 2010The Impact of Prostate Biopsy and Periprostatic Nerve Block on Erectile and Voiding Function: A Prospective Study Tobias Klein, Rein Jueri Palisaar, Alexander Holz, Marko Brock, Joachim Noldus, and Andreas Hinkel Tobias KleinTobias Klein , Rein Jueri PalisaarRein Jueri Palisaar , Alexander HolzAlexander Holz , Marko BrockMarko Brock , Joachim NoldusJoachim Noldus , and Andreas HinkelAndreas Hinkel View All Author Informationhttps://doi.org/10.1016/j.juro.2010.06.021AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We evaluated the effect of multiple core prostate biopsy and periprostatic nerve block on voiding and erectile function. Materials and Methods: A total of 198 patients in whom prostate cancer was suspected were randomly assigned to undergo 10-core prostate biopsy with (71) or without (74) periprostatic nerve block. The 53 men with a history of negative prostate biopsy underwent 20-core saturation prostate biopsy with periprostatic nerve block. The International Prostate Symptom Score and International Index of Erectile Function were completed before, and 1, 4 and 12 weeks after biopsy to measure changes in voiding and erectile function, and quality of life. Upon prostate cancer diagnosis patients were excluded from further analysis. Results: The International Prostate Symptom Score was significantly increased in all patients at week 1, which persisted at weeks 4 and 12 after saturation biopsy (p = 0.007 and 0.035, respectively). After 10-core prostate biopsy with periprostatic nerve block patients had a higher International Prostate Symptom Score at weeks 4 and 12 but this was not statistically significant (p >0.05). Quality of life was significantly affected at all times after saturation prostate biopsy (p = 0.001, 0.003 and 0.010, respectively). International Index of Erectile Function scores decreased significantly in all groups at week 1 (p <0.05). The decrease persisted at week 4 in each 10-core prostate biopsy group. Conclusions: Prostate biopsy causes impaired voiding. Saturation prostate biopsy and periprostatic nerve block seem to have a lasting impact on voiding function. Erectile function is transiently affected by prostate biopsy regardless of periprostatic nerve block and the number of cores. Patients who undergo prostate biopsy must be informed about these side effects. References 1 : Random systematic versus directed ultrasound guided transrectal core biopsies of the prostate. J Urol1989; 142: 71. Abstract, Google Scholar 2 : Ultrasound guided transrectal core biopsies of the palpably abnormal prostate. J Urol1989; 142: 66. Link, Google Scholar 3 : Systematic 5 region prostate biopsy is superior to sextant method for diagnosing carcinoma of the prostate. J Urol1997; 157: 199. 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Link, Google Scholar Department of Urology, Ruhr-University-Bochum, Marienhospital Herne, Herne, Germany© 2010 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byFainberg J, Gaffney C, Pierce H, Aboukhshaba A, Chughtai B, Christos P and Kashanian J (2020) Erectile Dysfunction is a Transient Complication of Prostate Biopsy: A Systematic Review and Meta-AnalysisJournal of Urology, VOL. 205, NO. 3, (664-670), Online publication date: 1-Mar-2021.Whitson J, Murray K and Thrasher J (2016) Prostate Biopsy is Associated with an Increased Risk of Erectile DysfunctionJournal of Urology, VOL. 196, NO. 1, (21-23), Online publication date: 1-Jul-2016.Pham K, Johnston R, Jeldres C, Lewinshtein D and Porter C (2014) The Impact of Multiple Prostate Needle Biopsies on Long-Term Erectile DysfunctionUrology Practice, VOL. 2, NO. 2, (85-89), Online publication date: 1-Mar-2015.Braun K, Ahallal Y, Sjoberg D, Ghoneim T, Dominguez Esteban M, Mulhall J, Vickers A, Eastham J, Scardino P and Touijer K (2013) Effect of Repeated Prostate Biopsies on Erectile Function in Men on Active Surveillance for Prostate CancerJournal of Urology, VOL. 191, NO. 3, (744-749), Online publication date: 1-Mar-2014. Volume 184Issue 4October 2010Page: 1447-1452 Advertisement Copyright & Permissions© 2010 by American Urological Association Education and Research, Inc.Keywordsprostatic neoplasmsurination disordersbiopsyimpotenceprostateMetricsAuthor Information Tobias Klein More articles by this author Rein Jueri Palisaar More articles by this author Alexander Holz More articles by this author Marko Brock More articles by this author Joachim Noldus More articles by this author Andreas Hinkel More articles by this author Expand All Advertisement PDF downloadLoading ...
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