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The genome of the model beetle and pest Tribolium castaneum

2008; Nature Portfolio; Volume: 452; Issue: 7190 Linguagem: Inglês

10.1038/nature06784

1476-4687

Stephen Richards, Richard A. Gibbs, George M. Weinstock, Susan J. Brown, Robin E. Denell, Richard W. Beeman, Richard Gibbs, Gregor Bucher, M. Friedrich, Cornelis J.P. Grimmelikhuijzen, Martin Klingler, Marcé D. Lorenzen, Siegfried Roth, Reinhard Schröder, Diethard Tautz, Evgeny M. Zdobnov, Donna M. Muzny, Tony Attaway, Stephanie Bell, Christian Buhay, Mimi N. Chandrabose, Dean Chavez, Kerstin P. Clerk-Blankenburg, Andrew Cree, Marvin Dao, Clay Davis, Joseph Chacko, Huyen Dinh, Shannon Dugan-Rocha, Gerald Fowler, Toni T. Garner, Jeffrey Garnes, Andreas Gnirke, Alica Hawes, Judith Hernandez, Sandra Hines, Michael Holder, Jennifer Hume, Shalini N. Jhangiani, Vandita Joshi, Ziad Khan, LaRonda Jackson, Christie Kovar, Andrea Kowis, Charles Lee, Lora Lewis, Jon Margolis, Margaret Morgan, Lynne V. Nazareth, Ngoc B. Nguyen, Geoffrey Okwuonu, David L. Parker, San Juana Ruiz, Jireh Santibanez, Joël Savard, Steven E. Scherer, Brian Schneider, Erica Sodergren, Selina Vattahil, Donna Villasana, Courtney White, Rita Wright, Yoonseong Park, Jeff Lord, Brenda Oppert, Susan E. Brown, Liangjiang Wang, George M. Weinstock, Yue Liu, Kim C. Worley, Christine G. Elsik, Justin Reese, Eran Elhaik, Giddy Landan, Dan Graur, Peter Arensburger, Peter W. Atkinson, Jim Beidler, Jeffery P. Demuth, Douglas W. Drury, Yu Zhou Du, Haruhiko Fujiwara, Vincenza Maselli, Mizuko Osanai, Hugh M. Robertson, Zhijian Tu, Jian-Jun Wang, Suzhi Wang, Henry Song, Lan Zhang, Doreen Werner, Mario Stanke, Burkhard Morgenstern, Victor Solovyev, Peter Kosarev, Garth Brown, Hsiu Chuan Chen, Olga Ermolaeva, Wratko Hlavina, Yuri Kapustin, Boris Kiryutin, Paul Kitts, Donna Maglott, Kim D. Pruitt, Victor Sapojnikov, Alexandre Souvorov, Aaron J. Mackey, Robert M. Waterhouse, Stefan Wyder, Evgenia V. Kriventseva, Tatsuhiko Kadowaki, Peer Bork, Manuel Aranda, Riyue Bao, Anke Beermann, Nicola Berns, Renata Bolognesi, François Bonneton, Daniel Bopp, Thomas Butts, Arnaud Chaumot, Robin E. Denell, David Ferrier, Cassondra M. Gordon, Marek Jindra, Que Lan, H. Michael G. Lattorff, Vincent Laudet, Cornelia Von Levetsow, Zhenyi Liu, Rebekka Lutz, Jeremy A. Lynch, Rodrigo Nunes da Fonseca, Nico Posnien, Rolf Reuter, Johannes B. Schinko, Christian Schmitt, Michael Schoppmeier, Teresa D. Shippy, Franck Simonnet, Henrique Marques‐Souza, Yoshinori Tomoyasu, Jochen Trauner, Maurijn van der Zee, Michel Vervoort, Nadine Wittkopp, Ernst A. Wimmer, Xiaoyun Yang, Andrew K. Jones, David B. Sattelle, Paul R. Ebert, David R. Nelson, Jeffrey G. Scott, Subbaratnam Muthukrishnan, Karl J. Kramer, Yasuyuki Arakane, Qingsong Zhu, David G. Hogenkamp, Radhika Dixit, Haobo Jiang, Zhen Zou, Jeremy L. Marshall, Elena N. Elpidina, Konstantin S. Vinokurov, Cris Oppert, Jay D. Evans, Zhiqiang Lu, Picheng Zhao, Niranji Sumathipala, Boran Altincicek, Andreas Vilcinskas, Michael J. Williams, Dan Hultmark, Charles Hetru, Frank Hauser, Giuseppe Cazzamali, Michael R. Williamson, Bin Li, Yoshiaki Tanaka, Reinhard Predel, Susanne Neupert, Joachim Schachtner, Peter Verleyen, Florian Raible, Kimberly K. O. Walden, Sergio Angeli, Sylvain Forêt, Stefan Schuetz, Ryszard Maleszka, Sherry Miller, Daniela Großmann,

Insect-Plant Interactions and Control

Tribolium castaneum is a member of the most species-rich eukaryotic order, a powerful model organism for the study of generalized insect development, and an important pest of stored agricultural products. We describe its genome sequence here. This omnivorous beetle has evolved the ability to interact with a diverse chemical environment, as shown by large expansions in odorant and gustatory receptors, as well as P450 and other detoxification enzymes. Development in Tribolium is more representative of other insects than is Drosophila, a fact reflected in gene content and function. For example, Tribolium has retained more ancestral genes involved in cell–cell communication than Drosophila, some being expressed in the growth zone crucial for axial elongation in short-germ development. Systemic RNA interference in T. castaneum functions differently from that in Caenorhabditis elegans, but nevertheless offers similar power for the elucidation of gene function and identification of targets for selective insect control. The red flour beetle Tribolium castaneum is a common pest: a type of 'bran bug', it targets cereal products, including grain, flour and rice bran. It is also a commonly used laboratory model, combining the ease of systematic RNA interference experiments such as those used with the nematode worm C. elegans with a biology that is more representative of most insects than even Drosophila. This weeks sees the publication by the Tribolium Genome Sequencing Consortium of the genomic sequence of T. castaneum. This is the first beetle genome to be published, and it will be a valuable resource for insect development studies and pest biology. The beetle Tribolium castaneum is a commonly used laboratory model, combining the ease of systematic RNAi experiments like those in Caenorhabditis elegans, with biology that is more representative of most insects than Drosophila melanogaster. A large consortium has sequenced and analysed the genome of the red flour beetle, creating a resource for biologists everywhere.